Inexperienced-lipped mussel & osteoarthritis remedy: How one among nature’s strongest anti-inflammatories works
Are you involved about your canine’s mobility and joint well being? Dive into this weblog to get a greater understanding of the well being advantages of green-lipped mussel for canines and the way it will help relieve the signs of osteoarthritis and cut back using anti-inflammatory medication.
Mobility is the important thing component in holding our canine buddies wholesome and glad for a few years to come back. Considering again to my first canine, Skai, I used to be so grateful he was in a position to go mountaineering with us within the mountains even on the age of 15.
However whereas he appeared unstoppable, ultimately stiffness and aches began to set in. Seeing your canine decelerate is hard for any pet mother or father as mobility is every part for them — it is pleasure, freedom, and life itself.
Thankfully, there are pure methods to help your canine’s mobility and improve their lifespan, one among them being the Perna mussel or green-lipped mussel.
In 2009, a research referred to as An evidence-based systematic review of green-lipped mussel (Perna canaliculus)(1) confirmed that New Zealand green-lipped mussel offers a clinically vital optimistic remedy impact on osteoarthritis (joint irritation).
This research included a assessment of 9 medical trials, specializing in the results of green-lipped mussels on OA ache and mobility, however additionally confirmed that green-lipped mussels improved gastrointestinal signs in OA sufferers taking non-steroidal anti-inflammatory drugs (NSAIDs) which are extensively utilized in human and veterinary medication. These medication are recognized to trigger gastrointestinal, kidney, and liver side effects, leading to a deeper imbalance within the physique.
However that is not all, what makes green-lipped mussels so useful for canines and folks lies within the highly effective vitamins it incorporates.
What makes green-lipped mussels so distinctive?
A current research carried out by a Japanese analysis group targeted on the compounds behind the green-lipped mussel’s optimistic results on joint well being, ache administration, and mobility — the bioactive glycosaminoglycans (GAGs)(2).
Marine invertebrates comparable to mussels are a wealthy supply of those extremely sulfated and uncommon glycosaminoglycans. Perna canaliculus is likely one of the greatest sources produced on a big scale in New Zealand.
The glycosaminoglycans from the green-lipped mussel, primarily chondroitin sulfate (CS) and heparan sulfate (HS), exhibit a number of notable organic results:
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Encouraging nerve progress: Sure chondroitin sulfate chains, particularly these with a selected sort of sugar pairing (GlcA-GalNAc(4,6-O-disulfate)), have been discovered to assist in the creation of connections between nerve cells. This discovery hints at potential makes use of within the fields of neurology and regenerative medication, the place selling nerve progress and restore is required.
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Joint well being and osteoarthritis remedy: Chondroitin sulfate is often used for its potential advantages in joint well being, notably within the remedy of osteoarthritis. It’s believed to contribute to the upkeep and restore of cartilage, the connective tissue that strains and cushions joints.
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Anti-inflammatory properties: Each chondroitin sulfate and heparan sulfate possess anti-inflammatory properties, that are useful in decreasing irritation in instances of arthritis.
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Tissue homeostasis (stability) and cell proliferation (creation and progress): GAGs play essential roles in mobile phenomena like cell proliferation, cell adhesion, differentiation, and tissue homeostasis.
One other research, this time analysing the effects of a diet enriched with green-lipped mussel in dogs with osteoarthritis(3), noticed that there was a major improve in Omega-3 fatty acids ranges of their blood after 60 days. The homeowners additionally reported enhancements of their canines’ ache and exercise ranges after switching to this weight-reduction plan.
Why I selected so as to add green-lipped mussel to JointButter
For these of you who’ve missed the newest information, JointButter, our new product and the world’s first fermented joint and mobility help complement for canines, will probably be quickly added to our product line up.
I’ve researched numerous vitamins, herbs, and superfoods for a few years with a purpose to give you the very best formulation that might make a transparent distinction for our canines’ joint well being and mobility.
That is how I got here throughout the green-lipped mussel and its highly effective anti-inflammatory and joint-repair properties. The glycosaminoglycans (GAGs) from Perna mussels have a novel construction and bioactivity, making it a preferred ingredient in canine and human mobility formulation.
Whereas I’ve additionally added chondroitin sulfate and glucosamine to JointButter, the addition of a whole-food supply of GAGs from Perna mussels considerably boosts the efficiency of the complement and will increase the spectrum of obtainable glycosaminoglycans.
How are green-lipped mussels raised and harvested?
Produced solely in New Zealand, green-lipped mussel manufacturing entails a number of steps.
Seeds are first collected and planted in a hatchery. As soon as they hatch into larvae, they connect themselves to rocks, lengthy ropes, and different arduous surfaces.
As soon as hooked up, a change into juvenile and consecutively into grownup mussels follows. Inexperienced-lipped mussels are able to be harvested in 26 to 48 months.
A notice on the sustainability of green-lipped mussel manufacturing
When formulating JointButter, my group and I didn’t simply deal with the standard and science-backed efficacy of the substances we chosen; we additionally paid shut consideration to their environmental sustainability.
The areas the place Perna mussels are harvested are underneath the stewardship of the producers in a profitable collaboration with Mussel Reef Restoration Belief and Revive Our Gulf Foundation.
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Inexperienced-lipped mussel for canines FAQ
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Are green-lipped mussels good for canines?
Sure, green-lipped mussels or Perna mussels comprise glycosaminoglycans, comparable to glucosamine and chondroitin that assist cut back irritation within the physique, restore and defend the cartilage, and promote optimum joint well being in canines.
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What are the unwanted side effects of inexperienced lipped mussel?
There aren’t any recognized unwanted side effects to supplementing your canine’s or pet’s weight-reduction plan with green-lipped mussels. Nevertheless, if your canine has an allergy to shellfish, it is best to strive this ingredient in small quantities when beginning this complement.
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Is inexperienced lipped mussel higher than glucosamine for canines?
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Is inexperienced lipped mussel higher than fish oil?
Fish oil is just not thought-about to be the identical as Perna Mussel resulting from completely different nutrient profile. As well as, fish oil is mostly unsustainable choice resulting from overfishing. Heavy-metal focus also needs to be a concern if you wish to defend your canine’s well being.
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Is Inexperienced Lipped Mussel Harvest sustainable?
Article references:
1. ”Inexperienced-lipped mussel assessment” by Catherine Ulbricht and group. PMID: 22435354 DOI: 10.1080/19390210802690191
2. “Bioactive glycosaminoglycans research” in Biochemical and Biophysical Analysis Communications, Quantity 612, 5 July 2022, Pages 50-56; Ayumu Mubuchi and group.